Meredith must save Thatcher’s life; Izzie empathizes with a tumor-riddled patient; annoyed with Cristina's competitive zeal, Mark tricks her into assisting on an odd surgery.
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During her chemo treatment, Kitty is thrilled when a surprise visitor comes to town; Sarah realizes that she must tell her kids about Luc; Holly finds a way to keep her financial future from unraveling; Kevin and Scotty agree on a possible surrogate.
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When the hospital lab tech, Isaac, discovers he has an inoperable tumor wrapped around his spine, he turns to Derek for help; Derek challenges Richard’s authority.
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The parents of Arizona’s 10-year-old patient offer the hospital a generous donation, but Arizona finds herself in a conflict of interest when the patient's condition worsens; Cristina tests her boundaries with Owen.
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Sarah’s new lover charms the entire family except Nora; during a difficult time, Nora finds that her new French houseguest is a great comfort; Robert tries to distract Kitty from cancer; Kevin and Scotty stumble onto an unexpected surrogacy candidate.
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