Matt tries to get rid of Sylar; Claire and Gretchen get hazed; H.R.G. and Tracey team up to save a teen from the consequences of his unchecked ability.
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Meredith must save Thatcher’s life; Izzie empathizes with a tumor-riddled patient; annoyed with Cristina's competitive zeal, Mark tricks her into assisting on an odd surgery.
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When the hospital lab tech, Isaac, discovers he has an inoperable tumor wrapped around his spine, he turns to Derek for help; Derek challenges Richard’s authority.
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The parents of Arizona’s 10-year-old patient offer the hospital a generous donation, but Arizona finds herself in a conflict of interest when the patient's condition worsens; Cristina tests her boundaries with Owen.
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Rusty and Dale continue to fight over their science project, while Casey and Ashleigh continue to work on getting ZBZ back to being the number one house with a musical number.
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