When Camiel, a gay dentist, and Simon, a carefree café owner, collide in a traffic accident, their lives become intrinsically entwined. When they bump into each other fourteen years later, Simon is severely ill. Camiel experiences at close range how Simon and those around him come to terms with his illness. The strength and humour that Simon shows in this difficult time leave a lasting impression on Camiel. Simon is a sexy, witty, emotional and life-affirming story of friendship and family, which shows that even through difficult times the love, strength, and humor of the ones closest to you can make life, no matter how brief, worth living.