The season opener finds Michael Scofield in Sona, a hellish and deadly Panamanian prison where a previous riot has forced all authority out and has left the prisoners in charge of their own lives (and deaths). With the fate of his loved ones hanging in the balance, Michael must to find Whistler, a mysterious fellow inmate hiding within the prison's sewer system, in order to break him out from a prison from which there is no way out. Meanwhile, Lincoln searches for a missing Sara and receives troubling news about LJ.
Time is running out, and Michael must enlist the help of his cellmate Sucre to help execute his elaborate escape plan. But Sucre wants no part of it and asks for a cell transfer, and Michael's new...
As the full-scale riot escalates, Michael faces a difficult decision regarding the life of Dr. Sara, and Abruzzi and Sucre team up to break the devil's back. Meanwhile, T-Bag tastes blood as his...
In order to get Abruzzi back in command of the prison's work detail -- and the escape plan back on track -- Michael must give up Fibonnaci's location to Philly Falzone. Meanwhile, Michael and Dr....
Dr. Sara and the escape gang are shocked to discover the identity of Michael's latest visitor, who brings him a priceless piece of the plan. Meanwhile, Captain Bellick becomes more suspicious and...
Abruzzi, Sucre and C-Note make a run for it on their own; Michael and Lincoln plan another breakout - this time to rescue a jailed LJ, whom Mahone targets in his quest to capture the escaped cons;...
Lincoln Burrows is scheduled to die on death row for an assassination his younger brother Michael is convinced he did not commit. With no other options and time running out, Michael takes drastic...
Kellerman and Hale pay a visit to Warden Pope, whose past may not be as angelic as it appears. Meanwhile, Michael learns he may be getting out of Fox River much sooner than he expected - without...
Westmoreland uses Bellick to plug a hole in the escape plan, which forces Michael to move up the breakout timetable. A fearful Tweener pledges his loyalty to Michael and in return may get out of...
Michael's plan hits a snag when he discovers an old storage shed crucial to the escape has been turned into a break room. Meanwhile, LJ goes on the lam and the conspiracy claims three more lives....
The mystery man reveals himself to Lincoln as well as his connection to some bad company; when Michael realizes Sara holds the key to the escape plan, he takes their relationship to another level;...
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